I believe you could scan directly into a spreadsheet. The scanner can be set up (or maybe is by default) to essentially replace keyboard input. You could scan a bar code directly into a cell in a spreadsheet. When testing our scanner, I have just opened a blank word processer page, and started scanning barcodes. The scanner just "types" the scanned bar code into the page, and even throws in a carriage return so that the next scan happens on a new line. This was all done with the default factory settings on the scanner.